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Albeit that this model seems to be a fairly close approach to the true role for inositols as insulin-sensitizers (Figure 2), data on supplementation with inositol derivatives might question whether IPGs are the only way for inositols to modulate insulin signaling

10.1016/j.bbagrm.2013.11.001 37 FoyerC

We also feel it is best to offer both options because we see clients as individuals, and decide what medication is best for them

Subjects eating at caloric surplus, training infrequently, or sleeping poorly wont see dramatic shifts in body composition even with perfect peptide administration